Abstract:
Objectives: To assess self-sampling HPV testing combining with the internet may serve as a primary cervical cancer screening method in low-resource settings, and to establish an internet self-sampling cervical cancer screening-management model.
Methods: 20,136 women aged 30~59 years with vaginal self-sampling HPV testing as primary screening on internet-based was performed in 13 provinces, municipalities of China. The women who participated in the screening registered on the screening website. A questionnaire was investigated the acceptance of self-sampling after self-sampling.
Results: Among 20103 women with qualified samples, 35.81% of them was remote areas, 37.69% of them was never-screened, 59.96% of them under-screened, 18.54% with a primary school education or below and overall high-risk HPV prevalence was 13.86%. In 8136 respondents, 95.97% of women felt self-collection was easy to operate, 84.61% had no discomfort when using a self-sampling brush, 62. 37% women were more likely to choose self-sampling for cervical cancer screening in the future, 92. 53% were willing to introduce to others around them. Multivariate analysis showed that the reliability of self-sampling and the easy degree of sampling were the independent influencing factors of selecting self-sampling (p<0.05), while no statistical significance was found in different age, education, occupation, gravidity, medical insurance, age of sexual initiation (p>0.05).
Conclusions: The Internet-facilitated self-HPV-testing screening and management model for cervical cancer prevention with large sample study is feasible and effective and can be used as a supplement to the traditional screening, especially in marginal areas with few medical resources, finally the coverage of cervical cancer screening will be significantly improved.
